To conclude with, dehydration and fatigue are interconnected in body physiology. Patients diagnosed with chronic fatigue syndrome often report dehydration, muscle cramps and dizziness. And for elderly people who are not well hydrated, tiredness and fatigue are notable symptoms. Patients having underlying problems, like cholera, dysentery, diarrhea and vomiting, exhibit both symptoms. For such cases, the medical problem should be addressed as soon as possible to avoid serious complications.