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Pituitary Gland Problems

Ashwini Kulkarni Sule
There are many serious conditions that result due to malfunctioning of the pituitary gland. Tumors are the most common of all pituitary gland problems. The story gives you relevant information regarding the same.
Pituitary gland is a small, pea-sized gland situated in the hollow of your nose, behind the nose bridge. It is attached to the hypothalamus by means of a small, thin stalk. Hypothalamus is situated at the base of the brain and is responsible for controlling the secretion of this gland.
It is rightly called the master gland, since it is responsible for controlling the functions of the other glands as well. Its malfunctioning can play havoc in the body and lead to to hormone imbalance. It has a number of associated problems, a few of which are given in the paragraphs here.

Tumors

When cells grow in an uncontrolled manner, they lead to the formation of tumors. A benign tumor is harmless, as it does not spread to other parts of the body; whereas malignant tumors are cancerous, as they invade other cells and destroy them.
Pituitary gland tumors are mostly benign in nature. In 50% of the cases, the tumors are non functional and go undetected for a very long time. However, functional tumors can be particularly harmful, as they are mostly of secretory nature. They secrete some or the other hormone. Needless to say, over secretion of any hormone can lead to several complications.
For instance, over secretion of thyroid hormone disrupts the metabolic activities of the body, whereas, over secretion of the adrenal hormone results in adrenal disorders. Similarly, tumors in ovaries or testes disturb the balance of sex hormones and may result in infertility.

Craniopharyngioma

This is a congenital condition, i.e., it is present since birth. In this condition, the cystic mass exerts pressure on the hypothalamus, causing it to lose control over the secretion of the gland.
A fast growing cystic mass is mostly found in children, whereas a slow growing cystic mass is more prevalent in adults. This is one of the common problems in children, as it interferes with the human growth hormone (HGH), affecting the onset of puberty. Symptoms of craniopharyngioma are blurred vision, headaches, and disruption of hunger and thirst pattern.

Rathkes Cleft Cyst

The pituitary gland forms through Rathkes pouch, which then closes itself in the fetal stage. The remnant of this pouch remains in the gland for the entire life. However, sometimes, this remnant is filled with fluid, resulting in the formation of cyst called Rathkes Cleft Cyst (RCC). This condition mostly affects adults rather than children.

Sheehan's Syndrome

This disorder results due to severe uterine hemorrhage during childbirth. The excessive blood loss due to hemorrhage deprives the gland of blood supply. This may damage the functioning of the gland and lead to hypopituitarism. Multiple pregnancies or placental abnormalities are mainly responsible for this condition.

Multiple Endocrine Neoplasia

This is a genetic disorder that affects only men and runs in the family. The disorder stimulates the formation of tumors in any one of the endocrine system's glands in the body.
Since there are no specific symptoms, most of the problems associated with this gland go undetected for a very long time. They are only detected by accident while diagnosing some other problems. Surgery, radiotherapy, and medical therapy are some of the solutions to problems of the pituitary gland.
Disclaimer: This story is for informative purposes only, and should not be used as a replacement for expert medical advice.