The posterior tibial nerve lies in the foot. It is present in the tarsal tunnel, the space between the sturdy bones and overlying tough fibrous tissue. Compression or entrapment of this part of the nerve is responsible for tarsal tunnel syndrome (just like a pinched nerve leads to carpal tunnel syndrome in the wrist). Fractures, bone spurs, ganglions, tumors, muscle impingement, or foot deformities can cause damage to this nerve.